Genetic Engineering and Diseases - Gene Drive & Malaria

Can you please fix your atom in the intro?! Its supposed to have two electrons on its first orbital not four

👍

@@dldez8590 thanks Einstein

only 42 likes wow

What if plasmodium develops resistance against the antibodies?

the rate of sarcasm is too high..😂

Mosquitoes don't have jobs. How are they supposed to pay for a wall?

its sarcasm u know?

They have jobs! We work to get money --> to make a living, buy food, home.. They work to get the living literally, by gaining life essence as their custom.

They evolve to steal wallets!!!

Sup

Don't mind me, just another commenter with no Subscribers passing through--- Wait, what are YOU doing here?!
At the bottom of the comment section, no less!

i should have assumed a educated man like you watches kurzegesagt

It'll be next to impossible and besides not all mosquitoes even suck blood. Plus other animals eat them so we'd need to get more flies to replace them or everything is fucked

Seeing this comment excited me more than the fact that Brad Pitt and Angelina Jolie broke up.

they stole my tatics bro

a wolf in a sheep’s clothing

Mosquitos: Draw x12,345,353,500 bitch

@@Bennahr_Fett lol

If you get malaria would you have ptsd also ?

I wonder if we could differ the genetic modified from regular

Thank you for your service!

TRIGGERED

In the second world war, they didnt call you a hero if you killed one nazi because there were millions of them... when your kill counter goes over 1 billion, then we'll call you a hero ;)

But the admin(human) are too busy

Fortunately, one of the players has found the console.
(Dropping the joke, at least humans found C.R.I.S.P.R. & CAS9)
[Edit removed ambiguity]

70jcarbon thats called overwatch nerfing XD

David Allen said he is only provide any service or the trash container itself it was her first day on the phone fighting with Westgate shopping mall and the best part he wearing it like Now Wal-Mart shut down for the other families such a tragedy for
me the pic of the
other
illusion
that was given but most
illusion
of course you have to show it to the next level and I know it but you continue
loving it up tonight or tomorrow night with the correct names and stuff like the orange 58 chairs for you have become 8th and chairs sometime.

God: -Buffed Immune System

You've given me a cause to believe in humanity thank you.

Sheeshh...
W Singapore, let's hope Malaysia and Indonesia do the same

​@@onlyms4693Malaysia actually did this too, though not the whole Malaysia, mostly KL

what that

@@smiley5836 cuz thalassemia/ sickle cell anemia gives u somehow an Immunity to malaria

@@AlOqab_ bc of the shape of the blood cells the malaria cant hide itself

Makes sense to me 👍

Makes sense

-_________-

100% plausible

[sad dead meme noises]

Really good visuals and brief but acknowledging facts!

Yep

Tell me how they change the DNA then....

mainly i _LOVE_ the visuals. they can even make a boring lecture fun

If school was like this I'm pretty sure everyone would become an Einstein but the government doesn't give a shit.

you are terrible

come the fuck on

What's up man?

ceiling man.

Would make sense if we're destined for Type-1 civilization.

For real? Great news

what happened sorry ive been hiding in cave im confused

@@ayasya. same, never heard about it , but i'm happy about it

wait really?

What I haven't heard about this. I hope this is a good thing and it doesn't back fire final last words sorry I had to

how do you think we should do that?

Same reason of how we are eradicating mosquitos well eradicating the diseases Mosquitos spread. But I don't know if when someone is given CRISPR it's genetic. That's my only question

not why,what could we alter to help the bees?

Make the bees more resistant to pesticides that are currently killing them?

i don't think you can just flip a switch in their DNA or add something like that the only i see them building a resistance to that stuff is by evolving by themselves but im not a scientist im a student that's training to be a doctor behind a screen with a keyboard and im not too caught up on the subject of DNA

Weird finding you here xD

hi grande!

Why are you here lol.

it's not there fault.

yup same here

pussy

Goosebumps of happyness?

Mitglied der Pilzarmee oh yeah maybe

Its sexually arousing

?

true true

Good point. By doing so they could get a clearer idea about how fast the trait gets passed on and how long it will take to change the whole population

Yes, I had the same exact idea in mind.

the problem is that an "enclosed environment" large enough to properly model it would be huge, costly, take years, and possibly not be accurate because of the lack of other factors like actual humans to bite (and use to spread the disease) among other things. (you can't put humans in there because they would die. putting this here because inevitably somebody will say "well then just put those other factors in")

I've sure that's been done countless times by now. What we don't know is how this stuff works when it's released into the open environment.

Don't forget vaccines

Although I don't, I see why. TheY have different opinions than the kurzgesagt team

people who hate genetic modification

Parents/Religious people who believe that vaccines cause autism.

People who held their phones upside down

mosquitoes hated this vid.

Need a skin of that in csgo

I guess gene editing is a....double edged sw- ok i'm out.

AlliedExplore, kill all misquotes, effect all organisms, all organisms die because no misquotes, barley any organisms die because of misquotes, they are so popular they are a prime food source for many organisms, but it’s malaria we need to wipe out.

How do i give all my money to the investigations so they will kill Malaria ;-;
I'm sure that they van kill it but they don't have money :(

Did you say, *A E S T H E T I C*

That’s what I said when a video from this channel called The Most Efficient Way To Destroy The Universe came up on my recommended

Phew

@@Jensenrobinb ikr

Funny enough, I lived in Africa when I was a kid due to my parents being missionaries. I got Malaria once, and that was probably the most miserable week of my life as I felt terrible just standing up, and vomiting was frequent. Though as you can see, I'm not dead, so I suppose that's good. Though a missionary lady that I knew passed away because of Malaria.
Personally I wouldn't use the Gene modification for mosquitos though.

@@bluejacket4429 why not? You don't want others to avoid the terrible experience you had?

@@fernandorobinson8272 It's terrible, yes. But it's avoidable and survivable. It's hard to do either of those in a 3rd world country, but it isn't the only solution. Gene modification is the easy way out, and one of the biggest impacts it'll have is on the food chain. A lot of animals need mosquitoes for food, and I don't know how well they'd do without them.

I feel that way too

James Lupei the production is high quality indeed

Every time I watch a Kurzgesagt video, I feel like I have to rethink a lot of my views and ethics

@Paddy Lawn that is like the opposite of school

lol

Speak for yourself.

Congratulations! Nice work!

Congratulations!

Good job! Bet your teachers didn't know that this is already researched! I didn't have a clue and I'm a biology teacher. But I'm definitely going to teach my kids about that. Sooooo interesting!

@@PhoebeJaneway Yes, you should definitely teach students these things. I hate teachers because they are just teaching boring things. I learn more from youtube than books/teachers.

@@erek But on the other hand: some things are boring and STILL have to be learned like maths, history and politics, a foreign language and some basics in chemistry. Life isn't (oh what's the English term) a "Wunschkonzert" .....ah, there's no English idiom like that....So: Life in our modern world isn't always about what you want. And that's a lesson teachers should teach their students and thus make them strong for this world, don't you think?

@Mohammad Al Arab You can do it for military purpous, like colour it for camo in military. So yea you're just a sand dumbass

@robizzlor i wish you know

@robizzlor dumbass

Well at least you dont use it as camflouge, also you can say the same thing for fur coats except some don't kill the animal and only try to get the fur of the animal.

Are you calling yourself a cow?

You are from that animal channel right

Tierzoo knows how this engine works

the update is under development the video just said that

The game is supposed to be challenging tho, else there will be no fun, and in any case the "Modern Medicine" exploit is too OP anyway.

Anunay ikr humans are becoming too end game

Daniel A Freeman I just came here like 5 minute ago and already have orgasm.

ikr

IKR he kinda sounds like Morgan Freeman

Daniel A Freeman yay

+Rick McBigbolt I don't think he sounds like Morgan Freeman, but he does sound amazing in his own way. For one, MF has an American accent :D

watch crash course.

You should have known all of this

yeah, I just started today!

Fuckin' know right

I agree, me too

Fun fact: Biontech, the company which invented the covid vaccine Cominarty in cooperation with Pfizer, announced that they will try to develope a Malaria Vaccine with the help of MRNA Technology.

I think they are being released in some places

I did not know that was how that was spelled. German is so confusing sometimes.

Dankeschön: Thank you very much, Thank you.
Translated from German

@@yukinaproductions5647 the zombie apocalypse is upon us my friend

I hope more do

-.-

I hope both of you do next time you watch a video
from malaria

I hope I do.

Hhhh. Negativity.

They're electric. The wings are solar panels.

🤣

wow

Omg

Does this mean elon musk's dream come true?

It is a TV show.

EMP Boss
Really? What channel?

EMP Boss I agree

EMP Boss this helps me learn while TV is just a distraction to me.

Who watches TV now that we have internet?

Mosquito v2.13.45
+ Added 3 different sizes
+ Mosquito can now be coloured
+ 30% more annoying
- Removed malaria

XD

And it can always come with unwanted glitches.

@@TakingThisWay very true

And you can never uninstall the mod.

baguette

Moldy baguette

'let your dream come true.'

what if we did it wrong and made something far worse??

yesterday you said tomorrow

agreed

Yah

it's written parasites, not paracites

catvee lol

right

Wait, they count as cute?

but they r cute

catvee Mosquitoes. Check the spelling

Where's the fun in that tho?

EXACTLY! I've read up about CRISPR, but my input should never have any real weight on the debate to use or not use it. Only qualified (let me repeat that, QUALIFIED) scientists should decide. I say that because there's a lot of bad science going on out there (check John Oliver's report on scientific research).

I have to disagree. Scientists used to universally agree on some very stupid and harmful things, and many still do. I think that anyone should be able to debate these topics as long as they bring valid criticism to the table. This technology is going to effect everybody on the planet at some point or another.

agreed with Yewtub, Scientists will think like scientists, if they are going to fuck up the world, let everyone get involved in a debate, because earth belongs to us all and whatever results occur, it will effect everyone

I feel like it will go the same way as antibiotics if we use it where we are met with a threat of a constantly changing threat so we try to stop but it just keeps changing to survive the changes

Cuteness lol it looks hideous

Lol same hahahahaha

Well, their bloodlust is pretty important for the survival of the species, and cuteness may affect how they distinguish between species, so although it is funny, they are two important factors that shouldn't be messed with!

@@micaelgarcia8532 cuteness LOL, they are HIDIOUS no matter which angle you see them with

@@saileshnaidu8102 Well, who said their cuteness levels were positive? they just remain unchanged :P

Then ask them to

tbh

Frixon same

Mine did, it makes no difference...

mine showed the measles video.

Good idea

Mosquito does even have a mouth to bite.

Hahaha

This man ate a mosquito to “retrieve” his blood

**No try search in English**

my minecraft parody with 770 views has more dislikes (this video 21 my video has 23)

yea there's a reason for that. this channel has a team of pros.

Their finger slipped. KRplus should really leave some space between rating buttons.

Actually I did accidentally dislike the video, good thing I came back an hour to look at the comments, right?

Its like giving a free restaraunt 1 star despite the food being good. Haters gonna hate. Potatoes gonna potate

Sure, but we'd have to make abso-fucking-lutely certain that the test population is completely sealed in.

One of my friends is starting cutting edge research on Wolbachia very soon, hopefully in December we will have a video on this :)
they have done tests with very positive results

*reduced scale*. That's the problem.

they know the parasite can adapt. the problem is how fast the imune population will spread and how fast the parasite will adapt. its like a roulette, you can make a estimation, but there is no way to be sure.
maybe the numbers will say that the estimate time of the imune population become dominant is higher than the probability of the parasite mutate, but then the improbable happen and one single parasite end up adapting just before the old population is eradicated and suddenly all effort is in vain

I commented before watching to the end, I automatically assumed this was about Wolbachia which is going to be a groundbreaking bacteria which lives in many insects and can be engineered to stop the spread of zika and malaria :)

just because one thing didnt kill us all doesnt mean something else we dont understand wont

that's why Mitchell noted "as long as this stuff is used carefully"

i think if we don't try we'll never know. we don't stop using hammers because they can be used to bash someone's head in, and we don't stop using scissors because you can stab someone with them. with great reward comes great risk, of course, and no corners should be cut, but this could be to genetic engineering as the combustion engine was to transportation

+Mitchell Anthony the question is not wether we should try it or not. the question is when shoukd we use it and is it ready to use, is more research needed ? the fact that we already set off a nuke is a bad argument and false reasoning. its nog because bad things happened we should continue doing things recklessly.

Your parallel examples fall short in the nature that using a hammer or a nuke is a one time event. Whereas if we introduce this new genome to the genepool it will be self-replicating, and expanding. And we cannot know for sure WHAT will happen exactly.

Bro, this stuff is this good because of the time they take to make it. Better this than rushed, low quality half baked videos.

Look at the animation is all little pieces carefully stacked

That takes ages

+santisan
You can't bake videos, dude! They would melt :(

Making these videos is not easy. It takes time, research, animation, editing, voice acting. You can't just open premiere and click the "make video" button and be done

Congratulations you are safe from coronavirus now

They fear if the gene go wrong and it can't not be reverse back again

it the gene goes wrong, let us sing a song. we will dieeee from zombies. and then everything WILL be screwed up.

F, and its been so long since this video was made, its most likely been tested for bad side affects, they should use it, if karen doesnt make a facebook blog so bad that it stops it, FUCK KARENS, and i havent had any bad disease or virus before, but i know its really bad because even common diseases are horrid, so i hope you have recovered well

As someone who has died from malaria, I second this

Ikr

Well but what if we create a super mosquitoe by mistake, would you want that?

@@agentc7020t would be easier to kill.

I think the same. Lot of ethics for mosquitos but we have killeds billion of other inocents animals

Well, in fact we can.

Same lol

Rest In Peace XD

Checking in a month later, did you die? XD

o3o snake?
Q3Q SNNNNAAAAAKKKKKEEEEE!!!

Bro u ok?

Emmm. Noup. Mexican here. El mosco exist. Is a regular fly. You mean "El Moscote"

"ito" "o" "ote"

@@arcangelonmagus4239 oh OK, well then, I guess my Spanish is getting a little rusty lol

@@HelloTher1313 don't worry, he said mexican spanish, than it's so different from Spanish, "mosco" it's a good joke for a person from Spain, because we don't have that word, there's one so similar "mosca" in English "fly(insect)"

@@nomellameshomerollamamehomer oh, I guess my Spanish isn't that bad then 😀 thanks for telling me, I forgot how much the different versions of Spanish vary lol, I learned the version most common in Spain

It could be a great kurzgesagt mascot. Like the master sword.

It's a DNA sword or something

it's the legendary gene slicer. You need a logic skill of 90 or over and level 50 or over to even equip it!

It's not an ordinary sword it's excalibur. Only the king can wields it.

It looks like Fierce Deity's sword.

I imagine they're probably anti-GM rather than pro malaria.

It's just a joke bro

Probably, as we all know GMO's are unnatural and therefore bad.... malaria is natural and by the exact same logic must therefore be good................. like arsenic, uranium, and anthrax; all natural stuff is good.

I know, also nuclear weapons using naturally occurring elements, and our friend radiation

Thats not the case Anti-GMO supporters dislike the process, because GMO is reletivily new, so we don't know the effects of a long term "GMO-heavy society." I personally think there is far more to gain with GMO than without it, especially with food. There is no way we can feed a population of over 7 billion people with natural methods of cultivating food, GMO makes plants far more resistant to weather and that lets them grow in more environments and seasons. But we don't know how this effects the ecosystem in the long run. Both sides have good points, its not like one side is blatantly retarded.

Exactly. This video represents the changing of mosquitoes but not actually harming them.

#Mosquitoesisareligionofpeace

#mosquitosarefuckingannoyingandicanthaveamomentspeaceoutsidewithoutthembitingmeforcingmetogobackinside

Exactly, mosquitoes don't kill anyone, only their pathogenic payload does. The only kind of person this would hurt would be someone who can't make additional blood, which would always result in a miscarriage anyway.

All religons are "religons of peace." No religions are peaceful. If there are super insane followers of any religon, they will do harm. (Islam just has the most insane people)

why is every fantastic youtube video now spoilt by the same shitty copy pasted youtube comments

Because: humans

Because people need their fake internet points.

Because KRplus is dead

because people won't stop giving the spammers attention

Mr. Jellyfish
*laughs in leather boots*

@@maguyonseanlewis7696 lmao😆😆🤣

Mr. Jellyfish mate i do that all the time but the main point of it is to not waste eat the meat use the skin and waste as little as possible.

You don't kill animals from the inside.

Laughs in FnAF 5 language

Nicolo John B. David well said!

Nicolo John B. David indeed. Politicians do things that give them recognition and popularity, not things that are wise and right. The decision should be made by non-sided commission of the best scientists who know the topic, messing with nature is risky.

Nicolo John B. David No shit sherlock

Agreed. What the fuck does trump know about genetic modification?

Terezi Pyrope Agreed.

and other insect transmitted disease

against parasites :'( those poor mosquitos didn't ask for it :c

Name of a new Call of Duty lol

More like the Fierce Deity's sword.

+WanderingRandomer you've put it best(even if you were just joking about the shape), Crispr is not the/a sword of evil's bane, but rather a dramatically powerful tool however it might be used.

Oh boy! It was nice of the princess to invite us to have spaghetti!

thats why we have biosafety commitee to look after it..and to select which is good for all of us and nature

Hello, even if used for this purpose has some danger. This has to be applied together with the education of the population, especially those living in tropical forests. For the planet's population is increasing even with fatal diseases. Without them people have to know how to use contraceptive methods. Otherwise the population will grow at a faster rate.

and poorventry will raise among the world

sont you mean malario lmao