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- 게시일 2024. 04. 26.
- Toxicologist Anne Chappelle is back to answer more of the internet's burning questions about poison. What makes poison, well, poisonous? What the screaming heck is sun poisoning? How long does poison take to work? Can poison expire? Anne answers all these questions and much more!
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I like the explanation, ‘if it bites you and you die, it’s venomous; if you bite it and you die, it’s poisonous.’ I actually think it sums it up pretty clearly.
"If it bites you and it dies, you are poisonous. If you bite it and dies, you are venomous"
"If you bite it and it bites you and neither of you die, that's kinky"
@@aalisredwood What happens if it bites itself and I die?
@@controllingthemedia That's voodoo
@@controllingthemedia that's voodoo 😅
@@IreneWY 😅 ok but now you made the perfect case for them inviting a cultural anthropologist who specializes in tribal belief systems and rituals.
"If the lead singer is Bret Michaels then I'm sure it is Poison". That had me laughing for ages 🤣
Wasn't expecting it to be followed up with an MCR reference, but a very pleasant surprise!
But if it's just bad medicine, then it's Bon Jovi🤭🤣🤭
😆
That part went over my head
Might need Holy Water. .38 Special
I wish that when people talked about types of skin damage, they'd acknowledge what that looks like for people with darker skin. we don't get red rashes after sunburn. even my darkest bruises are often difficult to spot because of hyper-pigmentation. the stages of healing for cuts looks vastly different because we don't see the same change in colors around the wound sight. not to mention when you look for images to identify clinical signs, 99% of those images are of lighter skin and only marginally helpful to us looking to identify potentially serious medical issues.
Omg I never thought of that!!! Dang....
The thing is, most of these tests and medical studies have been done primarily on white people, so doctors and toxicologists genuinely don’t know the differences in darker skin because they’ve never learned about that. When all medical knowledge that these doctors have is based on white people, it can be very dangerous to poc, and even if the doctors have good intentions, sometimes it’s not enough
What an important issue.
That’s actually also a rather big problem in general dermatology. On very dark skin types the presentation of several skin diseases is way more difficult to diagnose (and sometimes just way different altogether) as e.g. reddening and/or darkening on light skin has much more contrast than the same on very dark skin. Also e.g. the distribution of skin cancers types most frequently found also shifts based on (biological) ethnicity.
What can be done to make this more widely known? Or who do we talk to in order to get the situation to improve?
I love how she says that it is poison in the right dose, instead of the wrong dose.
Great catch, that’s an important detail.
@@TheCompleteMental As an organic chemist, I can tell you that the definition of what is poisonous, is the absolute opposite of relative. It is VERY specific. And how much of something is needed to create a poisonous effect, is also very specific.
@@AB-80X man, I worded that joke terribly the first time
Its because they can be used for good
if you really wanna kill them you give them the left dose too
She has a very effective way of delivering information in a way that is accessible. Love her!
She's also an adorable lady :)
her saying “it’s a poisonous mushroom. does it really matter which is the most poisonous?” made me cackle
I'm here geeking out, like she's SO good at this.
Yeah, if you're a three year old... Everyone should already know this information and if you don't; well, I guess natural selection will take care of itself.
@@kingfunk6754 so you know what sun poisoning is? Well I and my class and my family didn't know
My son had botox injections in his legs for years to relax his muscles enough so he could wear splits. He has cerebral palsy. It's crazy knowing that this life changing treatment is also the most dangerous poison.
The window between useless and poison is medicine!
@@POPPPUdane my son's name is, you guessed it, Alex...so seeing your comment was freaky lol
I’ve had good results with Botox for headaches.
"The dose makes the poison". It's a saying that I wish more people understand because a lot of people find some ingredient (like flouride) and freak out about it and post things like "The workers who move literal gallons of this stuff all day wear protective equipment, I will never use anything that contains it." It's so stupid, but so many people use that reasoning.
@@shadowscall7758 stuff builds up in the body over time though, and fluoride is one we come into contact very often for a lifetime
My mom would've gone nuts for you while I was growing up lol. Her big "parent fear" was toxic chemicals and me getting poisoned so she was always lecturing me about stuff under the sink and making sure I didn't touch the pesticides for the farm. Once she figured out she could call PBS and they'd send her Mr. Yuck stickers the house and barn were *covered* in them
Thank you! I remember Mr. Yuck, but I never knew where to get the stickers!!!
That's so cute 😂
T
Glad to see you here and not poisoned to death lol. She succeeded
Whats PBS?
@@inspieredanimal3809 Public Broadcast Station. It's children and family programming paid for by donations and tax dollars. They have educational cartoon characters like Mr. Yuck (beware of poisonous household materials), Louie the Lightning Bug (don't get electrocuted), McGruff the Crime Dog (a dog dressed like Inspector Gadget that teaches children safety tips), Smokey the Bear (camping safety and forest fire prevention) etc. They also used to show Bob Ross and Sesame Street but I don't know what they have now. It's been at least 20 years since I tuned in lol
The amount of excitement that surged through my veins when she said “Party Poison” is unreasonable.
EXACTLY !
@@xKDxx i rarely hear mcr jokes outside of the general community, so just hearing it out of blue just makes me squeal “WHA- WHU- MCR- WHAAAAAAAAAA?”
my jaw actually dropped, i was not expecting that reference
FELT SO HARD i was making a snack and when she said tht my head WHIPPED to look at my phone
THE FUTURE IS BULLET PROOF
Anne is so cool she makes me want to reevaluate my life choices and return to college to become a toxicologist.
I was thinking the same thing so I looked up what it takes, and I am definitely not becoming a toxicologist.
I concur
@@nessa734 college is a waste of money anyway, all the information you need is publicly available online
@@anomaly3215 to become professional such as doctor, nurse, lawyer, and other spesific professionals such as toxicologist, we definitely need college degree.
Make sure you’re smart enough not to tell people to wet rag mercury. You put a magnet on the floor and leave the room for a few hours. Come back and all the mercury will be on either end of the magnet. You can then dispose of the magnet and mercury in a bag as she said.
11:24
"Chaeyoung's slave asked..."
I frikcing choked. These usernames... 💀💀💀🤣🤣
not chaeyoung 😭😭😭
My husband got sun poisoning last year. All the symptoms you described. It was not fun. He said his sick were he got burned felt tight for a few months after. Luckily he is a nurse and he was able to give me advice on how to help him in his recovery.
Can confirm...NOT fun.
At lower latitudes the time to burn in the sunlight is much lower. Northern Europeans have to limit their sunlight exposure to no more than thirty minutes a day during the most intense sunlight hours when nearer the equator. The usual precautions of long sleeved shirts, wide brimmed hats, SPF 50 or higher sunscreen, umbrellas and hydration are recommended to prevent risk of heat exhaustion, heat stroke and death.
This happened to my sister once after she had been out on a lake all day without sunscreen. She got these awful big blisters on her shoulders and felt incredibly sick for days, she said it was like a really intense flu. We were all really worried.
Cold cream on the burned skin is also great. Experienced it.
If he is a nurse he can tell it is not called sun poisoning 🤦♂️
I laughed so hard about your comment about handling mercury: "We don't do that anymore". I had a vial of mercury in my toy chemistry set as a child. I handled it plenty. It's a wonder us Boomers survived childhood.
Me caveman. As child, play rock. Now, no play rock. Mmmmmrrrgrrph.
To be fair I think the leaded gasoline probably makes the mercury look like a walk in the park
@@eithnemelee2997 and the asbestos walls and lead paint
@@eithnemelee2997 unless it's organic (methyl) mercury. 2 drops on the skin has killed.
@@benf6822 You are confusing Dimethylmercury with Methylmercury. Both are toxic, but Dimethylmercury is toxic on a different level when it comes to exposure. After that, Dimethylmercury metabolizes into Methylmercury.
I would also like to point out that exposure to Dimethylmercury can be treated. The case of Karen Wetterhahn's death is in part because it was initially left untreated. The major issue is that the effects of the poisoning cannot be reversed.
I have not worked with it, but as an organic chemist who specialise in Chlorinated and Fluorinated Organophosphates, I do understand how a neurotoxic compound like Methylmercury affects the body.
You can tell she loves her job and I love that for her. Interesting facts i didn't know i needed! 😅
Not only that she’s a great professional and loves her specialisation, but she also has great presentation skills, so she knows how to communicate properly her ideas to non-specialists 😬
She’s one of Batman’s nemesis 😄
Poison Support is one of the more interesting ones of this series I'm glad to see Anne back in the seat and schooling us. Hoping for more!
This lady gets an A+ on the music puns. Truly tickled me!
Right! Hilarious. Good for her.
This lady knows what she's doing! I'm so impressed and she doesn't miss a beat when she starts answering each question. She also makes it sound so much easier than it is. I would love to have a teacher like her!
She prepares them, it’s not on the spot
The magic of editing
@@joewachs43 Editing would be useless without her knowledge, plus her skill of delivery.
People say Im toxic but maybe they just cant get enough of me 💁♀️
Or maybe you're a toxic person. Ew.
Brilliant.
not bad
I'm a pharmacist and I loved this! Glad she brought up Botox, it's a fun conversation to have with people who didn't know its origin.
It a good channel. I'm an organic chemist. I do wish she tried cater a bit more to adults as well. Her presentation does seem to be targeted very much towards kids. Lots of adults like chemistry and toxicology as well.
I was diagnosed with sun poisoning a long time ago and it has actually effected the way I react to heat believe it or not. The headache mimicked a aneurysm and at 1st that's what they thought but couldn't find 1 so said sun poisoning. As for heat sensitivity, its like it changed something in my chemistry permanently. If I get too hot then I have the same but milder reaction. I've found that so interesting.
Hey do you have white "freckles" too? I was told by a doctor once that they're tiny 3rd degree burn scars. I have normal pale-person freckles, then I have these white reverse -freckle spots.
@@evientually I do have some like that yes.
@@evientually Wow - THATS interesting - I’ve never known why I had white areas with freckles and most other areas they all meld together. I’ve burned badly as a child- loved being out in the sun- it just didn’t love me back 😃
Body keeps the score! Same thing happens with heat exhaustion & other heat-related injuries. Very interesting
@@krisg3984 I'm not 100% on it so please don't take it as gospel. Sometimes doctors are wrong, but it's an explanation that fits my experience really well. If I've had second degree burns to the extent that I have, it makes sense that there would be places where it was a little bit more intense...but the idea that that kind of trauma could happen to my skin and it NOT leave even minimal scars doesn't make sense at all.
Botox for migraines has changed my life. It's too bad it started as a cosmetic surgery because people typically don't understand right away when I say I'm going to get Botox shots that I mean in a medical way. My neurologist administers it, my insurance pays for it, it's legitimate and it has been the *only* thing that has helped my chronic migraines.
Ohmygoodness I'm so happy it worked for you!!! My brother had it done, but it didn't touch them 😭
That's fantastic that you found something that works! Many, me included, haven't found a great solution. Curious though, if ppl aren't so understanding (and even if they were) why do you bother to share that level of detail? Why not just say, I'm off to an appt... That's what I do! With that, no explanation needed, no one in my business. :) I'm not in the habit of sharing my medications with ppl, so that makes it easy - no need to explain. For ppl you want to explain the whole shebang to for whatever reason, then do so, I guess, immediately explaining that it's for migraine treatment to head off the assumption that it's for cosmetic reasons. 🤷🏿♀️
Botox was created for a medical purpose and its patent sold bc its creators thought it would only see niche use! Like you said, though, it was popularized for its cosmetic uses.
More people are learning that it has other effects. Spreading that awareness, without shame, can help others know it too!
I remember watching a documentary like fifteen years ago about this guy whose neck contracted so that his head was always bent towards his shoulder. It ended up being Botox that let him finally hold his head upright.
She makes for an awesome college professor! I would never miss her class
Poison: You bit it.
Venom: It bit you.
My husband got sun poisoning a couple months ago, it was crazy….he was only in the sun without his shirt on for about an hour and a half, but that was enough. He was red for three weeks, and got hundreds of tiny blisters on his back, was fatigued, got a fever, and was kind of wrecked for a few days. His skin still prickles and feels like it has minor nerve damage. Do not recommend👍🏻
She's so positive she missed that one person's death wish.
I was just thinking that.
Anne is absolutely the aunt I would love in the family, could listen to these types of questions and answers for days 💛 well done!
Smart and witty toxicologist, who loves her rock music 🤘
Dr. Chappelle has a awesome personality which makes all these topics super interesting. She has her own podcast btw (it's a toxicology called Adverse Reactions). I've also talked to her on mine, she was a super fun guest and she can make complex topics understanding for dummies like me
I wonder why we stopped using Brompton Cocktails? I'm gonna look into that now. Just letting someone spend their last hours high, chatty and happy sounds very humane compared to our current end-of-life protocols.
I wanted to be a toxicologist once, couldn't hack it at the rigorous schooling but man this stuff is so cool.
The My Chemical Romance refrence blew my mind. Soon as she said Party Poison i was like....thats an MCR thing. And then she went there and i made an audible WWHHHAAATTTT
Bahahahaha Brett Michaels, Bon Jovi, Chemical Romance......awesome..
Thanks for the terrific and informative video.
She's literally one of my favorite people you guys have had on your channel.
Lmfao this lady rules. Definitely my favorite of the series. Very informative and clear but with a super fun personality
When I was twelve my older siblings thought it would be funny to get me drunk. I got alcohol poisoning and was so sick that I cannot abide it now.
Sort of did you a favour in the long run
I am so sorry alcohol is no joke especially at that age 😓
Funny situation though becuase now you are better off if you avoid drinking entirely.
"Bad Medicine" is a great song.
This lady's got taste
So is Party Poison
I've had death caps grow in my garden... here in Australia... of course lol. Most Australians (at least where I live) are taught to NEVER eat wild mushrooms. Some indigenous elders and mushroom experts know how to tell but death caps look almost identical to edible brown mushrooms found in woods in Asia and Europe. They even have signs in Chinese as a fair few Chinese tourists died after eating them.
This comment is much more relevant this month !
@@voseerie1439here looking for this comment 😅
I'm glad to hear that felt tip pens don't have enough toxin to harm a person. My youngest sister, for whatever reason, bit and sucked dry Crayola markers. She was pretty little at the time, but it was frustrating when I wanted to color a picture only to find out a marker vampire got to them first. 🧛♀🖍😂
According to my former colleague who is an art therapist, Crayola markers are non-toxic😳 and if I remember correctly other Crayola products (crayons, colored pencils, etc.) are non-toxic as well
Crayola (and generally most kids art supply makers) take the fact kids will destroy anything and put it in their mouths, so the products are designed to not harm kids.
That makes me think of Bunnicula. It was a bunny vampire, but instead of blood, he drank red. He ate a lot of tomatoes that turned white, lol.
hahaha best comment so far
Anne is great!
She is direct, charismatic, funny and straight forward, great to see her back!
The quickest, albeit not comprehensive explanation on venom and poison I have heard is:
If it bites you and you die, it was venomous. If you bite it and you die, it was poisonous.
Though my native language doesn't really make that distinction anyways, we only really have an umbrella term for toxins.
If it bites you and it dies, you are Chuck Norris
In my native language the word for poison and illicit drugs is the same word
I didn't know sun poisoning was a thing but it makes total sense, thinking about it. UV light is a form of radiation and it'd be even worse on us if the atmosphere wasn't able to weaken it.
Lupus gives you a similar reaction. I can’t be out in the sun for very long without getting red splotches on my skin & being in pain. I stay covered up, especially in the summer.
What a relief to find someone who knows toxicology and can explain these principles so quickly! Substances, chemicals, molecules, interactions, exposure methods, effects, transmission, history.
I was often sun-poisoned as a child; come to find out, I have primary Sjögren’s syndrome, and get photosensitive rashes and systemic illness after being out in the sun.
Photosensitivity is no joke. I lived in a far northern climate most of my life and had no idea how photosensitive I was. Only got full sun poisoning my first summer in the new house, but now I am insanely careful about any UV exposure.
(Just jokes I promise) are you also allergic to garlic and invisible in mirrors??
This lady is hilarious lol I don’t think I’ve ever seen someone make so many jokes yet barely crack a smile 😂
I remember when I got sun poisoning as a kid… (I only applied my sunscreen once & didn’t reapply after getting out of the water and then getting back in.) I had to stand in a cold shower for 15 minutes just to be able to stand without wanting to throw up. It’s not joke-use sunscreen!!
NOT THE KPOP USERNAME CHAEYOUNGSSLAVE 💀💀💀
I’ve always remembered Poison = Ingested, Venom = Injected
I've had sun poisoning one time....that was enough for me. I forgot to bring sunscreen to the pool once. My skin was so burnt that parts were purple. I temporarily lost vision and hearing on the 2nd day. Both finally came back by the end of the day. I was so sick as well. Never did this again!
I loved the first video and watched it multiple times. Was so excited and happy to see her back again for a second part! Something about the way she explains and answers these questions that is so engaging an fun. More please! haha
Not gonna lie, I love how botox was explained here.
A close friend of mine has cerebral palsy and botox is used in order to assist the muscles contraction amongst other things, so it was kinda cool to hear it referred to in the sense of "people use it for reasons"
I kinda wonder how mercury guy is doing, getting his question answered 4 years later
One thing I really wish she had mentioned, she talked about overdoses and tolerance. A typical opioid overdose, the issue is people with stop breathing, as opiates slow breathing so when you take enough, breathing stops and at that point you aren't awake to breathe consciously usually. But, if someone had a high enough tolerance, say a methadone patient who used heroin on top of it or something, could there be a point where the opiates themselves were toxic to the body? Not in the sense of an overdose, where respiratory depression is the issue, but in the sense of the drugs themselves being a poison to the body. I imagine that would happen at some point, but would it be feasible that a human could have a tolerance that high? There are definitely people out there that regularly consume enough drugs that would kill the average person but I've always wondered if there was an upper limit on how much drugs someone could do regardless of tolerance.
6:38 Her pronunciation of "Ik hou van jou" had me rolling. 😂
It means: "I love you", in case anyone is curious.
When I was in ninth grade Physical Science our teacher had a big container of mercury and he would have us stick our hands in it to see how it felt. None of us, including him had any idea how poisonous it was.
How did it felt tho
That's what happens when professors only know their material and have no general knowledge.
Thanks for bringing Anne back, she informs in a reassuring tone, love itttttt!
I love how everyone is always asking for a friend😂
Thank you for the comment on E. Coli food poisoning. Last month I ate at a McDonald's and 6 hours later the symptoms kicked in, going for 2 days over. Learned my lesson, never eating fast food again, warned the local sanitary defense of my town and my friends.
It was likely the lettuce actually - commercial pre-washed salad leaves and also bean sprouts are major e. coli vectors. It's caused by the water used for washing being contaminated. Supermarkets have had frequent outbreaks, it's actually pretty uncommon in fast food because fries etc don't tend to carry it.
However unless you were hospitalized and a local outbreak of e. coli specifically was confirmed, it was probably something else - certainly it's highly unlikely for it to only last two days. My guess would be campylobacter via poultry.
That sounds more like a staphylococcal poisoning which is one of the most frequent cause for self-limiting diarrhoea in the context of food poisoning
Ah, this is all so interesting and she’s great at explaining her knowledge. Love to see her expertise.
Just saw the the first poison support video and suprised to see that a second was uploaded hours ago. I now like to watch these kinds of videos. They are very educational!
Yes!!! I need a part 2. She is SO interesting! Thank You!
My first major outbreak of poison ivy as an adult was very bad. I swelled up like a frog (mostly my legs) and needed all kinds of drugs, steroids, NSAIDs, allergy pills, etc. Then a little while later, after it was gone, we went to the deep south on vacation where it's hotter than hades and I broke out in a rash all over my legs and I couldn't figure it out! I thought maybe it was just the heat. Well, I'm sure that didn't help, but it's nice to know there's a known reason for it. That episode was the first and it really triggered my sensitivity to poison ivy bad. I've caught it in the middle of winter before.
Love that you came back for round two, very fun!
Loved Anne's first video! So glad she's back!
I love learning everything with WIRED
The band references killed me😂 I need someone like her in my life
Love how articulate and confident she is. Goals.
So informative. The questions on the most part was excellent too.
What a cool gal! I really like how conversational she is- like an interesting person you’d meet at a bar.
This is the best toxicology video I’ve seen so far! Well done! I could totally use this for my forensic science students! Thank you for making this!
I'm very glad she brought up that botox has medical uses! It's often stigimatizing and/or treated as purely cosmetic, when in fact conditions such as interstitial cystitis can be helped with botox in the bladder.
This is why I read the comments, I didn't know about this. Down the research hole I go, thanks!
Very educational, thanks for sharing
can we have part 3 please? just being straightforwardly interested here.
I love these videos, i totally forgot about them, and was recommended again to me today, I'm glad! This lady is really cool.
This is really good information. Special thank-you for telling me that I may have problems if I'm off a medication for a while (after developing a resistance to it) and then take it again at the same high dose. It makes perfect sense, and I did not know about it.
She's awesome! Explained everything very well with a little bit if sass. I honestly never knew I was getting sun poisoning instead of a sun burn. I have very fair and sensitive skin so (even with sun screen) if I stay out in the sun too long (ie Sea World) I get blisters.
My grandmother worked with her husband at a lighthouse on the Great Lakes in the 1950s. The big lights where housed on an open bed of mercury. It was my grandmother's job to clean the debris that would get in the mercury by straining it by hand. Who knows what kind of damage it did to her.
Oh wow -- ! Thanks for sharing that ,
I got sun poisoning at the beach one summer , l I had hives to break out on my chest , an awful upset stomach , and felt super lethargic. You can get too much of a good thing I learned.
Bursted out laughing when she said chaeyoung slave lmaooo
Today I've learned the new word - "sun poisoning" (so far I've known only "heat stroke")
loved this lady, thanks for having her back! :D
When I was in college studying hazardous materials, we read a great book called, "The Dose Makes the Poison".
I’m very surprised when she spoke about snake venom she didn’t reference the differences in venom. There are snakes that have a hemotoxin which attacks your blood cells and cause you to bleed out and then there are snakes with neurotoxins which affect your nervous system and paralyzes your diaphragm and heart.
And then there’s the South Pacific Cone Snail. Terrifying
I think there's just too much information for one video so they have to cut somewhere
because the type of venom is irrelevant. it’s toxic regardless
@@misseselise3864 but then how would you know which antivenin to use??
@@icarusbinns3156 You have to be able to identify the snake that bit you, or at least be able to describe it to doctors.
Veritasium made a good video about venom: krplus.net/bidio/Z96hiaKgl4S9pKQ
Anne Chappelle the legend back at it again!
Thanks for sharing interesting news and facts and info
Anne is such an engaging speaker, she has such a great way of explaining things
Clear explanations very informative thank you
Would be cool if she could go in-depth into organofluorosphates. She already talked about Acetylcholine inhibitors so it wouldn't be too much of a stretch.
Alright, WIRED you hear that?
I've been waiting for this one!!
Thanks! That was educating!
Thank you, this is indeed helpful
This lady is definitely a good entertainer and explainer! 10/10 charisma :D
the mcr reference made me very happy. love her!
Lessons that I never thought I needed. Thanks
I'm really enjoying your videos! Thank you :D
speaking of hemlock, it is growing rampantly around my neighborhood, is there a way I can have some agency come and remove it? or is it ok as long as my dog doesn't sniff, touch, walk by, brush up against... and what if he does and is unaffected because its on his fur and I touch him getting the toxics on my skin, it really freaks me out and I am super paranoid going out for walks around here.
Hemlock is really only an issue if someone decides to eat it, you might want to inform any neighbours with kids to be careful around it and keep an eye on your dog, but you and your dog will be fine if you touch it.
Hemlock is unique in the way that its toxin concentration on leaves, roots, every part of the plant changes over the time span of the entire day and night, so some people might actually chewed the leaves of Hemlock and survived and think that the toxin level of Hemlock is exaggerated. You should make a video about how dangerous Hemlock is.
She has a comforting energy ☺️
I love her personality and intelligence! I'm glad they bring her back
My dad would tell me how back when he was in school in the 70s, the science teacher would pour mercury out onto the lab table and let them examine it.
I like learning more about toxicology my favorite subject
Shes such a good science communicator, i could listen to her talk for days!!
Yaaaaay! Anne's back for round 2! She's so cool.